This Patient Information leaflet summarizes the most important information about Imitrex. If you would like more information, talk with your healthcare provider. You can ask your healthcare provider or pharmacist for information about Imitrex that is written for healthcare professionals. Imitrex tablets are a serotonin 5-HT 1 receptor agonist "triptan". It works by narrowing blood vessels in the brain, which helps to relieve migraines. Imitrex Injection is a prescription medicine used to treat acute migraine headaches with or without aura and acute cluster headaches in adults who have been diagnosed with migraine or cluster headaches. opek.info risperdal
Ask your healthcare provider or pharmacist for a list of these medicines if you are not sure. Heart Rate: Transient increases in blood pressure observed in some patients in clinical studies carried out during sumatriptan's development as a treatment for migraine were not accompanied by any clinically significant changes in heart rate. Imitrex is a registered trademark of the GlaxoSmithKline group of companies. The injection is intended to be given subcutaneously, and intramuscular or intravascular delivery must be avoided. Instruct patients on the proper use of IMITREX STATdose Pen and direct them to use injection sites with an adequate skin and subcutaneous thickness to accommodate the length of the needle.
Respiratory Rate: Experience gained during the clinical development of sumatriptan as a treatment for migraine failed to detect an effect of the drug on respiratory rate. What should I discuss with my healthcare provider before using sumatriptan? Sumatriptan belongs to a group of drugs called triptans. It affects a certain natural chemical serotonin that constricts blood vessels in the brain. It may also block other pain pathways in the brain. Migraines: One type of drug, called triptans, is the mainstay of migraine treatment. They include eletriptan Relpax naratriptan Amerge rizatriptan Maxalt sumatriptan Imitrex, Zecuity zolmitriptan Zomig and others.
What are the ingredients in Imitrex Injection? Imitrex is not used to prevent or decrease the number of migraine headaches you have. Change in the sense of taste nasal spray. This does not prevent future or lessen how often you get attacks. Do not take a sumatriptan nasal capsule by mouth. It is for use only in the disposable nosepiece and special inhaler device that comes with this medicine.
This list is not complete. Other drugs may interact with sumatriptan, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. Use of this medicine for 10 or more days per month may exacerbate headaches; use a headache diary to record how often you have a headache and when you take this medicine. For patients with risk factors predictive of CAD who are determined to have a satisfactory cardiovascular evaluation, it is strongly recommended that administration of the first dose of sumatriptan injection take place in the setting of a physician's office or similar medically staffed and equipped facility. Because cardiac ischemia can occur in the absence of clinical symptoms, consideration should be given to obtaining on the first occasion of use an electrocardiogram ECG during the interval immediately following IMITREX Injection, in these patients with risk factors. Ask your health care provider any questions you may have about how to use Imitrex tablets. Six of these 8 patients had ECG changes consistent with transient ischemia, but without accompanying clinical symptoms or signs. Of these 8 patients, 4 had either findings suggestive of CAD or risk factors predictive of CAD prior to study enrollment. Triptans. These prescription drugs narrow your blood vessels. They're a fast-acting option for severe migraines. The risk of heart disease, liver disease, and high blood pressure increases with age. Older adults may be more sensitive to the side effects of this drug, especially increased blood pressure and heart problems. It is unknown what effect hemodialysis or peritoneal dialysis has on the serum concentrations of sumatriptan. Imitrex spray is not approved for use in CHILDREN younger than 18 years old. Talk with the doctor. Nasal spray: A 10 mg intranasal dose may be administered as 5 mg in each nostril. NSAIDs with them. Talk to your doctor before taking any over-the-counter meds if you take other medicines, supplements, or have any medical problems. The safety of treating an average of more than 4 headaches in a 30-day period has not been established. Do not stop taking any medications without consulting your healthcare provider.
How you think can affect how you feel. So finding ways to relax and stop negative thoughts may help prevent headaches. Tablets: White, triangular-shaped, film-coated, and debossed with “I” on one side and “25” on the other. Pedialyte, to replenish my electrolytes and minerals. Store your medicine away from light. Remove the nozzle from your nostril. Keep your head level for 10 to 20 seconds while gently breathing in through your nose and out through your mouth. Do NOT breathe in deeply. norvasc
Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. When your sharps disposal container is almost full, you will need to follow your community guidelines for the right way to dispose of your sharps disposal container. There may be state or local laws about how you should throw away used needles and cartridges. Open the Carrying Case lid. Our Imitrex Injection Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. ZecuityR was voluntarily withdrawn from the market by the manufacturer in June 2016 due to reports of serious application site reactions associated with use of this iontophoretic transdermal system. Since marketing of the patch in September 2015, there have been a number of reports in which patients describe severe redness, cracked skin, blistering or welts, and burns or scars where the patch was worn. Many report resolution within hours to weeks, although there are reports of unresolved skin reactions, typically skin discoloration. Skin: Infrequent were erythema, pruritus, and skin rashes and eruptions. Rare was skin tenderness. This may not be a complete list of all interactions that may occur. Ask your health care provider if Imitrex tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine. Put the Pen in the Cartridge Pack. HT1 agonists. Discontinue IMITREX Injection if these disturbances occur. Drug Interactions: Monoamine Oxidase Inhibitors: In vitro studies with human microsomes suggest that sumatriptan is metabolized by monoamine oxidase MAO predominantly the A isoenzyme. In a study of 14 healthy females, pretreatment with MAO-A inhibitor decreased the clearance of sumatriptan. Tell your doctor if you are or if you plan to become pregnant. You tend to get them at the same time each year, such as the spring or fall. Because of their seasonal nature, people often mistake for or business stress. Call your doctor if your headache does not go away at all after using the first sumatriptan dose.
How should I use Imitrex Statdose sumatriptan injection? The name of your medicine is IMITREX sumatriptan succinate Injection. It can be obtained only by prescription from your doctor. The decision to use IMITREX Injection is one that you and your doctor should make jointly, taking into account your individual preferences and medical circumstances. If you have risk factors for heart disease such as high blood pressure, high cholesterol, obesity, diabetes, smoking, strong family history of heart disease, or you are postmenopausal or a male over 40 you should tell your doctor, who should evaluate you for heart disease in order to determine if IMITREX is appropriate for you. Although the vast majority of those who have taken IMITREX have not experienced any significant side effects, some individuals have experienced serious heart problems and, rarely, considering the extensive use of IMITREX worldwide, deaths have been reported. In all but a few instances, however, serious problems occurred in people with known heart diseases and it was not clear whether IMITREX was a contributory factor in these deaths. Pen as shown in Figure B before you load a new Syringe Cartridge. The osmolality of both injections is 291 mOsmol. Imitrex Tablets. Such reactions can be life threatening or fatal. It is possible that some side effects of sumatriptan may not have been reported. Vagus nerve, since the headaches are immediately connected to the urge to have a bowel movement. purchase clavaseptin online with prescription
Focus your attention. Often forgetfulness may mean that you have too much on your mind. Slow down and pay full attention to the task you are doing now. Some MEDICINES MAY INTERACT with Imitrex spray. This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. A different medication may be necessary in that case. Some medicines can harm your baby. Each tablet contains sumatriptan succinate equivalent to 25 mg of sumatriptan. Imitrex spray should not be used to prevent or reduce the number of migraine headaches you have. If you have a headache that is different than your usual migraine headaches, check with your doctor before using Imitrex spray. To use Imitrex spray, remove the nasal spray unit from the plastic pack. Consult your doctor before -feeding.
Medication overuse headache may present as migraine-like daily headaches or as a marked increase in frequency of migraine attacks. Detoxification of patients, including withdrawal of the overused drugs, and treatment of withdrawal symptoms which often includes a transient worsening of headache may be necessary. Musculoskeletal: Acquired musculoskeletal deformity, arthralgia and articular rheumatitis, arthritis, intervertebral disc disorder, muscle atrophy, muscle tightness and rigidity, musculoskeletal inflammation, and tetany. Imitrex Injection also relieved photophobia, phonophobia sound sensitivity nausea, and vomiting associated with migraine attacks. Similar efficacy was seen when patients self-administered Imitrex Injection using the IMITREX STATdose Pen. You can take it as a pill or as a suppository if nausea or vomiting stops you from keeping anything down. Another form of ergotamine, called DHE 45 also treats them. You can get it as an injection or as a nasal spray. Patients who are advised to self-administer IMITREX Injection in medically unsupervised situations should receive instruction on the proper use of the product from the physician or other suitably qualified health care professional prior to doing so for the first time. Imitrex. See the end of this leaflet for a complete list of ingredients in Imitrex. Are the headaches triggered by something in your environment, such as smells, noise, or some kinds of weather? Treatment should be started at the first sign of a migraine headache, or associated symptoms such as nausea, vomiting, or photophobia; this drug should not be used for migraine prophylaxis. Imitrex spray is to be used only by the patient for whom it is prescribed. Do not share it with other people. Fast or slow heartbeat. IMITREX STATdose System NDC 0173-0739-02. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take see Drug Interactions section. Ottervanger JP, Vanwitsen TB, Valkenburg HA, Grobbee DE, Stricker BHC "Adverse reactions attributed to sumatriptan - a postmarketing study in general practice. Imitrex passes into your breast milk and may harm your baby. Talk with your healthcare provider about the best way to feed your baby if you take Imitrex. You should take preventive medicine, unless your headache periods last less than 2 weeks. Instruct patients to read the Instructions for Use before starting therapy. Provide patients instruction on the proper use of Imitrex Injection if they are able to self-administer Imitrex Injection in medically unsupervised situations. is there a generic pill for nootropil
Ear, Nose, and Throat: Deafness. How should I take Imitrex? Sumatriptan can affect your pupils during cataract surgery. Tell your eye surgeon ahead of time that you are using this medicine. Neither of these adverse events was associated with a serious clinical outcome. They may have fewer side effects than prescription drugs. Carcinogenesis, Mutagenesis, Impairment of Fertility: In carcinogenicity studies, rats and mice were given sumatriptan by oral gavage rats, 104 weeks or drinking water mice, 78 weeks. Nursing Mothers: Sumatriptan is excreted in human breast milk. Therefore, caution should be exercised when considering the administration of IMITREX Injection to a nursing woman.
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Have you ever had to stop taking this or any other medicine because of an allergy or other problems? Read this Patient Information before you start taking Imitrex and each time you get a refill. There may be new information. This information does not take the place of talking with your healthcare provider about your medical condition or treatment. Refill Cartridge Packs are available. generic naproxen order mastercard europe
If you are taking this product on a regular schedule and miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. If your medicine has expired the expiration date is printed on the treatment pack throw it away as instructed. Do not throw away your autoinjector. For subcutaneous injection only. Studies 2 and 3 the onset of relief was less than 10 minutes. Headache relief, as defined by a reduction in pain from severe or moderately severe to mild or no headache, was achieved in 70% of the patients within 1 hour of a single 6-mg subcutaneous dose of Imitrex Injection. Approximately 82% and 65% of patients treated with IMITREX 6 mg had headache relief and were pain free within 2 hours, respectively.
Breasts: Breast swelling, cysts, disorder of breasts, lumps, masses of breasts, nipple discharge, primary malignant breast neoplasm, and tenderness. Keep all away from children and pets. This drug should not be used for prophylaxis. Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. PREGNANCY and BREAST-FEEDING: It is not known if Imitrex spray can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imitrex spray while you are pregnant. Imitrex spray is found in breast milk. If you are or will be breast-feeding while you use Imitrex spray, check with your doctor. Discuss any possible risks to your baby. aromasin
Other News "AAN meeting: sumatriptan linked to life-threatening intestinal condition. If any of these effects persist or worsen, tell your doctor or promptly. If you did not get any relief after the first injection, do not give a second injection without first talking with your healthcare provider. This product contains salt sodium. Before using this drug, tell your doctor if you are limiting the amount of salt in your diet. Syringe Cartridge to the Cartridge Pack.